Stroke detection device developed at Penn named top 100 invention of 2022

Congratulations to Dr. Steve Messe, whose research efforts to develop a device to detect stroke in high-risk patients were recognized by TIME magazine as one of the 100 best inventions of 2022.

Neuralert: The 100 Best Inventions of 2022 | TIME E very 40 seconds, someone in the U.S. has a stroke.Early treatment is key to minimize adverse outcomes, yet a recent study of in-hospital strokes found that most go undetected for over four hours … time.com

WHAT WE’RE READING – JOURNAL CLUB

October 2022

Effect of Stenting Plus Medical Therapy vs Medical Therapy Alone on Risk of Stroke and Death in Patients With Symptomatic Intracranial Stenosis: The CASSISS Randomized Clinical Trial
Rivaroxaban in Patients with Atrial Fibrillation and a Bioprosthetic Mitral Valve
Rivaroxaban in Rheumatic Heart Disease-Associated Atrial Fibrillation
Prolonged Cardiac Monitoring and Stroke Recurrence: A Meta-analysis
Association of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence and Benefit From Patent Foramen Ovale Closure

ANA 2022 Chicago

Dr. Donna George presenting “Women’s Issues in Neurovascular Disease” at the American Neurological Association meeting in Chicago this month. Kudos!

Welcome to our 2022 fellows!

Sydni Cole, MD
Sydni attended medical school at Northwestern University Feinberg School of Medicine. She completed her neurology residency at Beth Israel Deaconess Medical Center. Sydni is joining us this year as a vascular neurology fellow.
Gbambele Kone, MD
Gbambele attended medical school at Weill Cornell Medical College.  He completed his neurology residency at Yale. Gbambele is joining us this year as a vascular neurology fellow. 
Nino “Nini” Kvantaliani, MD
Nini attended medical school at Tbilisi State Medical University in the country of Georgia, and then completed her neurology residency at Temple University. Nini is joining us this year as a vascular neurology fellow.
Sahily Reyes-Esteves, MD, PhD
Sahily attended medical school at the University of Puerto Rico and graduate school at the MD Anderson UTHealth Graduate School of Biomedical Sciences. She then completed a neurology residency at the Hospital of the University of Pennsylvania.   Sahily is joining us this year as a vascular neurology fellow.
Michela Rosso, MD
Michela attended medical school at University of Torino in Italy, and then completed her neurology residency at SUNY Downstate Health Sciences University in Brooklyn. Michela is joining us this year as a StrokeNET research fellow.

WHAT WE’RE READING – JOURNAL CLUB

JUNE 2022

Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation: The SETPOINT2 Randomized Clinical Trial
Recurrent Ischemic Stroke and Bleeding in Patients With Atrial Fibrillation Who Suffered an Acute Stroke While on Treatment With Nonvitamin K Antagonist Oral Anticoagulants: The RENO-EXTEND Study
Functional Outcomes of Patients ≥85 Years With Acute Ischemic Stroke Following EVT: A HERMES Substudy

WHAT WE’RE READING – JOURNAL CLUB

MAY 2022

Genetic Architecture of Stroke of Undetermined Source: Overlap with Known Stroke Etiologies and Associations with Modifiable Risk Factors
Comparison of tenecteplase with alteplase for the early treatment of ischaemic stroke in the Melbourne Mobile Stroke Unit (TASTE-A): a phase 2, randomised, open-label trial
Tenecteplase versus alteplase for the management of acute ischaemic stroke in Norway (NOR-TEST 2, part A): a phase 3, randomised, open-label, blinded endpoint, non-inferiority trial
Effect of Direct Transportation to Thrombectomy-Capable Center vs Local Stroke Center on Neurological Outcomes in Patients With Suspected Large-Vessel Occlusion Stroke in Nonurban Areas The RACECAT Randomized Clinical Trial
Accuracy of CT Perfusion–Based Core Estimation of Follow-up Infarction
Endovascular Treatment for Acute Ischemic Stroke With or Without General Anesthesia: A Matched Comparison

WHAT WE’RE READING – JOURNAL CLUB

MARCH 2022

Effect of Intra-arterial Alteplase vs Placebo Following Successful Thrombectomy on Functional Outcomes in Patients With Large Vessel Occlusion Acute Ischemic Stroke The CHOICE Randomized Clinical Trial
Safety and efficacy of aspirin, unfractionated heparin, both, or neither during endovascular stroke treatment (MR CLEAN-MED): an open-label, multicentre, randomised controlled trial
Risk of first ischaemic stroke and use of antidopaminergic antiemetics: nationwide case-time-control study